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Aside from genetic will cause of such syndromes, There's also instances where by the Snrpn/Ube3A cluster is intact but its genes are epigenetically misregulated. This is By way of example the situation if the two homologs of chromosome fifteen originate in the exact dad or mum, a ailment known as uniparental disomy (UPD). Maternal UPD is chargeable

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